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Mantle, D and Hargreaves, IP (2024) Coenzyme Q10 and Autoimmune Disorders: An Overview. International Journal of Molecular Sciences, 25 (8). pp. 1-17. ISSN 1661-6596
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Abstract
Some 90 autoimmune disorders have been described in medical literature, affecting most of the tissues within the body. Autoimmune disorders may be difficult to treat, and there is a need to develop novel therapeutic strategies for these disorders. Autoimmune disorders are characterised by mitochondrial dysfunction, oxidative stress, and inflammation; there is therefore a rationale for a role for coenzyme Q10 in the management of these disorders, on the basis of its key role in normal mitochondrial function, as an antioxidant, and as an anti-inflammatory agent. In this article, we have therefore reviewed the potential role of CoQ10, in terms of both deficiency and/or supplementation, in a range of autoimmune disorders.
| Item Type: | Article |
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| Uncontrolled Keywords: | 0399 Other Chemical Sciences; 0604 Genetics; 0699 Other Biological Sciences; Chemical Physics |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Pharmacy & Biomolecular Sciences |
| Publisher: | MDPI |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 23 Apr 2024 10:35 |
| Last Modified: | 23 Apr 2024 10:45 |
| DOI or ID number: | 10.3390/ijms25084576 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/23126 |
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