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Coenzyme Q10 and Autoimmune Disorders: An Overview

Mantle, D and Hargreaves, IP (2024) Coenzyme Q10 and Autoimmune Disorders: An Overview. International Journal of Molecular Sciences, 25 (8). pp. 1-17. ISSN 1661-6596

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Some 90 autoimmune disorders have been described in medical literature, affecting most of the tissues within the body. Autoimmune disorders may be difficult to treat, and there is a need to develop novel therapeutic strategies for these disorders. Autoimmune disorders are characterised by mitochondrial dysfunction, oxidative stress, and inflammation; there is therefore a rationale for a role for coenzyme Q10 in the management of these disorders, on the basis of its key role in normal mitochondrial function, as an antioxidant, and as an anti-inflammatory agent. In this article, we have therefore reviewed the potential role of CoQ10, in terms of both deficiency and/or supplementation, in a range of autoimmune disorders.

Item Type: Article
Uncontrolled Keywords: 0399 Other Chemical Sciences; 0604 Genetics; 0699 Other Biological Sciences; Chemical Physics
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Pharmacy & Biomolecular Sciences
Publisher: MDPI
SWORD Depositor: A Symplectic
Date Deposited: 23 Apr 2024 10:35
Last Modified: 23 Apr 2024 10:45
DOI or ID number: 10.3390/ijms25084576
URI: https://researchonline.ljmu.ac.uk/id/eprint/23126
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