Tools
Tools
Beaumont, AJ, Campbell, AK, Unnithan, VB, Oxborough, D, Grace, F, Knox, A and Sculthorpe, NF (2024) The Influence of Age and Exercise Training Status on Left Ventricular Systolic Twist Mechanics in Healthy Males-An Exploratory Study. Journal of Cardiovascular Development and Disease, 11 (10).
|
Text
The Influence of Age and Exercise Training Status on Left Ventricular Systolic Twist Mechanics in Healthy Males An Exploratory Study.pdf - Published Version Available under License Creative Commons Attribution. Download (1MB) | Preview |
Abstract
Age-related differences in twist may be mitigated with exercise training, although this remains inconclusive. Moreover, temporal left ventricular (LV) systolic twist mechanics, including early-systolic (twistearly), and beyond peak twist (twistpeak) alone, have not been considered. Therefore, further insights are required to ascertain the influence of age and training status on twist mechanics across systole. Forty males were included and allocated into 1 of 4 groups based on age and training status: young recreationally active (YRA, n = 9; 28 ± 5 years), old recreationally active (ORA, n = 10; 68 ± 6 years), young trained (YT, n = 10; 27 ± 6 years), and old trained (OT, n = 11, 64 ± 4 years) groups. Two-dimensional speckle-tracking echocardiography was performed to determine LV twist mechanics, including twistearly, twistpeak, and total twist (twisttotal), by considering the nadir on the twist time-curve during early systole. Twisttotal was calculated by subtracting twistearly from their peak values. LV twistpeak was higher in older than younger men (p = 0.036), while twistpeak was lower in the trained than recreationally-active (p = 0.004). Twistpeak is underestimated compared with twisttotal (p < 0.001), and when early-systolic mechanics were considered, to calculate twisttotal, the age effect (p = 0.186) was dampened. LV twist was higher in older than younger age, with lower twist in exercise-trained than recreationally-active males. Twistpeak is underestimated when twistearly is not considered, with novel observations demonstrating that the age effect was dampened when considering twistearly. These findings elucidated a smaller age effect when early phases of systole are considered, while lower LV systolic mechanics were observed in older aged trained than recreationally-active males.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ageing; cardiac mechanics; echocardiography; exercise; left ventricle |
| Subjects: | R Medicine > RC Internal medicine > RC1200 Sports Medicine |
| Divisions: | Sport and Exercise Sciences |
| Publisher: | MDPI |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 11 Nov 2024 11:06 |
| Last Modified: | 11 Nov 2024 11:15 |
| DOI or ID number: | 10.3390/jcdd11100321 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/24730 |
 |
View Item |