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Immunotherapy and Cancer: The Multi-Omics Perspective

Donisi, C, Pretta, A, Pusceddu, V, Ziranu, P, Lai, E, Puzzoni, M, Mariani, S, Massa, E, Madeddu, C and Scartozzi, M (2024) Immunotherapy and Cancer: The Multi-Omics Perspective. International Journal of Molecular Sciences, 25 (6). ISSN 1661-6596

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Abstract

Immunotherapies have revolutionized cancer treatment approaches. Because not all patients respond positively to immune therapeutic agents, it represents a challenge for scientists who strive to understand the mechanisms behind such resistance. In-depth exploration of tumor biology, using novel technologies such as omics science, can help decode the role of the tumor immune microenvironment (TIME) in producing a response to the immune blockade strategies. It can also help to identify biomarkers for patient stratification and personalized treatment. This review aims to explore these new models and highlight their possible pivotal role in changing clinical practice.

Item Type: Article
Uncontrolled Keywords: Humans; Neoplasms; Immunotherapy; Tumor Microenvironment; Biomarkers, Tumor; Precision Medicine; Multiomics; AI; biomarkers; immunotherapy; multi-omics science; state of the art; Humans; Multiomics; Neoplasms; Immunotherapy; Biomarkers, Tumor; Precision Medicine; Tumor Microenvironment; Orphan Drug; Immunization; Precision Medicine; Cancer; Vaccine Related; Immunotherapy; Rare Diseases; 5.1 Pharmaceuticals; Cancer; 3 Good Health and Well Being; Humans; Multiomics; Neoplasms; Immunotherapy; Biomarkers, Tumor; Precision Medicine; Tumor Microenvironment; 0399 Other Chemical Sciences; 0604 Genetics; 0699 Other Biological Sciences; Chemical Physics
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Biological and Environmental Sciences (from Sep 19)
Publisher: MDPI
SWORD Depositor: A Symplectic
Date Deposited: 29 Nov 2024 10:34
Last Modified: 29 Nov 2024 10:45
DOI or ID number: 10.3390/ijms25063563
URI: https://researchonline.ljmu.ac.uk/id/eprint/24932
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