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Mantle, D, Rowbottom, H, Jones, J, Potts, IM, Turton, N, Dewsbury, M, Lopez-Lluch, G and Hargreaves, IP (2024) Energy Metabolism as a Therapeutic Target in Cancer: The Role of Coenzyme Q10. Oxygen, 4 (2). pp. 122-138.
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Energy Metabolism as a Therapeutic Target in Cancer The Role of Coenzyme Q10.pdf - Published Version Available under License Creative Commons Attribution. Download (659kB) | Preview |
Abstract
The generation of energy within cells is a fundamental process enabling cell survival, and as such it represents a potential target in cancer therapy. In this article, we therefore review the relative contributions of glycolysis and oxidative phosphorylation/mitochondrial function to cancer cell energy generation, and we highlight their respective potential value as chemotherapeutic targets. This article is particularly focussed on the potential role of coenzyme Q10 in the prevention and treatment of cancer.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 3101 Biochemistry and Cell Biology; 32 Biomedical and Clinical Sciences; 3211 Oncology and Carcinogenesis; 31 Biological Sciences; Cancer; Prevention; Nutrition; Cancer; 7 Affordable and Clean Energy |
| Subjects: | Q Science > QH Natural history > QH301 Biology R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Pharmacy and Biomolecular Sciences |
| Publisher: | MDPI |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 05 Mar 2025 16:10 |
| Last Modified: | 05 Mar 2025 16:15 |
| DOI or ID number: | 10.3390/oxygen4020008 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/25796 |
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