Cohort Profile: The Nijmegen Exercise Study (NES)

Van Der Sluijs, KM, Bakker, EA, Schoofs, MCA, Vloet, JIA, Verbeek, ALM, Hopman, MTE, Thijssen, DHJ ORCID: 0000-0002-7707-5567 and Eijsvogels, TMH (2025) Cohort Profile: The Nijmegen Exercise Study (NES). International Journal of Epidemiology, 54 (4). ISSN 0300-5771

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Abstract

The Nijmegen Exercise Study (NES) provides a longitudinal collection of data on lifestyle characteristics and the development and progression of chronic diseases. The NES is a population-based cohort enriched with highly physically active individuals. The cohort contains individuals both with and without chronic diseases, with physical activity levels ranging from inactive to extremely active. Baseline data collection is ongoing. Since 2011, baseline data have been collected in 23 643 participants with a mean age of 48.7 years (range: 18–94) of whom 46.0% are female. Annual follow-up data have been collected in 11 484 participants (48.6%) with a median follow-up duration of 8.0 (5.0, 10.9) years. Additional, centre-based evaluation is ongoing and has so far been performed in a subset of 1743 participants. Baseline and follow-up questionnaires provide trends in demographics, socioeconomic status, lifestyle characteristics, medical history, medication use, and historical and current physical activity and sedentary behaviour. Centre-based evaluation includes anthropometrics, blood pressure, arterial stiffness, carotid artery characteristics, venous blood biomarkers, accelerometer-based physical activity patterns, handgrip strength, and 4-metre gait speed. Data are available to scientific researchers upon request. Please contact the corresponding author (Thijs.Eijsvogels@radboudumc.nl) for data availability inquiries and visit our website for additional information (www.radboudumc.nl/nes).

Item Type:	Article
Uncontrolled Keywords:	4202 Epidemiology; 4206 Public Health; 42 Health Sciences; 4905 Statistics; 49 Mathematical Sciences; 0104 Statistics; 1117 Public Health and Health Services; Epidemiology; 4202 Epidemiology; 4206 Public health; 4905 Statistics
Subjects:	R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions:	Sport and Exercise Sciences
Publisher:	Oxford University Press (OUP)
Date of acceptance:	11 June 2025
Date of first compliant Open Access:	12 August 2025
Date Deposited:	12 Aug 2025 13:38
Last Modified:	12 Aug 2025 13:45
DOI or ID number:	10.1093/ije/dyaf092
URI:	https://researchonline.ljmu.ac.uk/id/eprint/26924

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