Does it hold weight? The perceived effects of contraceptive use on weight status in females: A mixed-methods study

Bass, L, Prostináková, T, Silang, KG orcid iconORCID: 0009-0009-1200-7326, Griffiths-Gray, A, McQuilliam, S orcid iconORCID: 0000-0002-4987-5938, Mahon, E, Whitehead, A orcid iconORCID: 0000-0003-0611-364X and Johnson, KO orcid iconORCID: 0000-0002-7395-5129 (2025) Does it hold weight? The perceived effects of contraceptive use on weight status in females: A mixed-methods study. Plos One, 20 (12). ISSN 1932-6203

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Open Access URL: https://doi.org/10.1371/journal.pone.0339323 (Published version)

Abstract

PURPOSE: To examine females' perceived effects of contraceptive use on weight management and to identify potential confounding factors that may contribute to perceived weight changes across their lifespan.

METHODS: Three hundred and fifteen predominantly UK-based females completed a questionnaire assessing the prevalence and type of current and previous contraceptive use, reasons for use, side effects experienced, and perceived effects on weight. Twenty-five participants who reported contraceptive use subsequently completed timeline interviews to gain deeper insight into the perceived impact of contraception on weight status and to identify contextual or lifestyle factors that may have contributed to perceived weight-management difficulties.

RESULTS: Contraceptive use prevalence was 88% among respondents, with 38% using a contraceptive method at the time of data collection. Forty-two percent reported greater difficulty managing their weight while using hormonal contraception compared with their natural menstrual cycle. In follow-up interviews, depot medroxyprogesterone acetate (DMPA) was consistently identified as the method most associated with difficulties in weight management. However, most participants attributed weight-related challenges to broader life circumstances, such as moving away from home, relationship changes, and stress, rather than contraceptive use alone.

CONCLUSION: Although 42% of females reported difficulty managing their weight while using contraception, these perceptions often reflected lifestyle factors rather than physiological effects of the contraceptive itself. Clinicians, coaches, and recreationally active females should consider the most appropriate contraceptive type for their circumstances and also reflect on life status and current events as potential contributors to perceived weight management struggles or weight gain. Individuals may want to consider alternative methods if they are initially affected by DMPA.

Item Type: Article
Uncontrolled Keywords: Humans; Body Weight; Contraception; Contraception Behavior; Life Style; Adolescent; Adult; Middle Aged; Female; Young Adult; Surveys and Questionnaires; Humans; Female; Adult; Body Weight; Young Adult; Middle Aged; Surveys and Questionnaires; Adolescent; Contraception; Contraception Behavior; Life Style; 3213 Paediatrics; 32 Biomedical and Clinical Sciences; Behavioral and Social Science; Clinical Research; Contraception/Reproduction; Women's Health; Nutrition; Prevention; Humans; Female; Adult; Body Weight; Young Adult; Middle Aged; Surveys and Questionnaires; Adolescent; Contraception; Contraception Behavior; Life Style; General Science & Technology
Subjects: R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Sport and Exercise Sciences
Publisher: Public Library of Science (PLoS)
Date of acceptance: 4 December 2025
Date of first compliant Open Access: 15 January 2026
Date Deposited: 15 Jan 2026 15:06
Last Modified: 15 Jan 2026 15:06
DOI or ID number: 10.1371/journal.pone.0339323
Editors: Dabla, V
URI: https://researchonline.ljmu.ac.uk/id/eprint/27914
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