Childhood Body Weight in Relation to Cause-Specific Mortality: 67 Year Follow-up of Participants in the 1947 Scottish Mental Survey.

Batty, GD, Calvin, CM, Brett, CE, Čukić, I and Deary, IJ (2016) Childhood Body Weight in Relation to Cause-Specific Mortality: 67 Year Follow-up of Participants in the 1947 Scottish Mental Survey. Medicine (Baltimore), 95 (6). ISSN 1536-5964

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Abstract

The association between childhood body weight and adult health has been little-examined, and findings are inconsistent.In a representative sample of the Scottish nation (the Scottish Mental Survey of 1947), we examined the association between body mass index measured at 11 years of age and future cause-specific mortality by age 77 years. In this cohort study, a maximum of 67 years of follow-up of 3839 study members gave rise to 1568 deaths (758 from cardiovascular disease, 610 from any malignancy). After adjustment for covariates, there was some evidence of a relation between elevated childhood body mass index and rates of mortality ascribed to all-causes (hazard ratio per 1 SD increase in body mass index; 95% confidence interval: 1.09; 1.03, 1.14), cardiovascular disease (1.09; 1.01, 1.17), all cancers combined (1.12; 1.03, 1.21), smoking-related cancers (1.13; 1.03, 1.25), and breast cancer in women (1.27; 1.04, 1.56).In conclusion, we provide further observational evidence for the need for weight control measures in youth.

Item Type:	Article
Uncontrolled Keywords:	1103 Clinical Sciences
Subjects:	R Medicine > R Medicine (General)
Divisions:	Natural Sciences and Psychology (closed 31 Aug 19)
Publisher:	Lippincott, Williams & Wilkins: Open Access Journals
Related URLs:	http://www.ncbi.nlm.nih.gov/pubmed/26871765
Date of acceptance:	16 November 2015
Date of first compliant Open Access:	22 June 2016
Date Deposited:	22 Jun 2016 08:48
Last Modified:	04 Sep 2021 04:15
DOI or ID number:	10.1097/MD.0000000000002263
URI:	https://researchonline.ljmu.ac.uk/id/eprint/3799

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