Montgomery, C and Fisk, JE and Wareing, M and Murphy, P (2007) Self reported sleep quality and cognitive performance in ecstasy users. Human Psychopharmacology: Clinical and Experimental, 22 (8). pp. 537-548. ISSN 0885-6222
Montgomeryetal2007 sleep.pdf - Accepted Version
Research suggests that ecstasy users exhibit psychobiological changes relative to nonusers such as altered sleep patterns and cognitive deficits. In turn, it has been suggested that sleep quality may be a mediator of such cognitive deficits in ecstasy users. The present study sought to investigate this proposed relationship.
Aspects of cognitive functioning in 104 ecstasy users and 103 nonusers obtained from our previous studies were reanalysed to explore the extent to which ecstasy-related group differences were attributable to differences in sleep quality. Cognitive function was assessed via the computation span test, consonant updating, paired associate learning, syllogistic reasoning and word fluency. Sleep quality was measured via the Epworth Sleepiness Scale (ESS), and the Karolinska Sleepiness Scale (KSS).
Ecstasy users performed worse than nonusers on all cognitive measures. While no differences were observed on the ESS, ecstasy users reported greater tiredness at the beginning of testing than nonusers. When the sleep variables were included as covariates, the effects of ecstasy on all cognitive measures remained significant.
The results of the present study suggest little evidence for the mediating effects of sleep on cognitive function in ecstasy users.
Keywords: ecstasy; MDMA; sleep; memory
|Additional Information:||This is the peer reviewed version of the following article: Montgomery, C., Fisk, J. E., Wareing, M. and Murphy, P. (2007), Self reported sleep quality and cognitive performance in ecstasy users. Hum. Psychopharmacol. Clin. Exp., 22: 537–548, which has been published in final form at http://dx.doi.org/10.1002/hup.879. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving|
|Uncontrolled Keywords:||1115 Pharmacology And Pharmaceutical Sciences, 1701 Psychology, 1702 Cognitive Science|
|Subjects:||B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RM Therapeutics. Pharmacology
|Divisions:||Natural Sciences and Psychology|
|Date Deposited:||15 May 2015 11:24|
|Last Modified:||15 May 2015 11:24|
|DOI or Identification number:||10.1002/hup.879|
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