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Jjunju, FPM, Damon, DE, Romero-Perez, D, Young, IS, Ward, RJ, Marshall, A, Maher, S and Badu-Tawiah, AK (2020) Analysis of non-conjugated steroids in water using paper spray mass spectrometry. Scientific Reports, 10 (1). ISSN 2045-2322
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Analysis of non-conjugated steroids in water using paper spray mass spectrometry.pdf - Published Version Available under License Creative Commons Attribution. Download (4MB) | Preview |
Abstract
A novel strategy for the direct analysis of non-conjugated steroids in water using paper spray mass spectrometry (PS-MS) has been developed. PS-MS was used in the identification and quantification of non-conjugated (free) steroids in fish tank water samples. Data shown herein indicates that individual amounts of free steroids can be detected in aqua as low as; 0.17 ng/µL, 0.039 ng/µL, 0.43 ng/µL, 0.0076 ng/µL for aldosterone, corticosterone, cortisol, and β-estrone, respectively, and with an average relative standard deviation of ca. < 10% in the positive ion mode using PS-MS/MS. Direct detection of free steroids in a raw water mixture, from aquaculture, without prior sample preparation is demonstrated. The presence of free steroids released in fish water samples was confirmed via tandem mass spectrometry using collision-induced dissociation. This approach shows promise for rapid and direct water quality monitoring to provide a holistic assessment of non-conjugated steroids in aqua.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QA Mathematics > QA75 Electronic computers. Computer science R Medicine > R Medicine (General) |
| Divisions: | Computer Science & Mathematics |
| Publisher: | Nature Publishing Group |
| SWORD Depositor: | A Symplectic |
| Date Deposited: | 05 Jun 2023 11:06 |
| Last Modified: | 05 Jun 2023 11:15 |
| DOI or ID number: | 10.1038/s41598-020-67484-7 |
| URI: | https://researchonline.ljmu.ac.uk/id/eprint/19617 |
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