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Standardising lipid testing and reporting in the United Kingdom; a joint statement by HEART UK and The Association for Laboratory Medicine

Kenkre, JS, Mazaheri, T, Neely, RDG, Soran, H, Datta, BN, Penson, P, Downie, P, Yates, AM, Hayden, K, Patel, M and Cegla, J Standardising lipid testing and reporting in the United Kingdom; a joint statement by HEART UK and The Association for Laboratory Medicine. Annals of Clinical Biochemistry. ISSN 0004-5632 (Accepted)

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Abstract

Atherosclerotic cardiovascular disease remains a major cause of premature death in the UK. Lipid testing is a key tool used to assess cardiovascular risk and guide clinical management decisions. There are currently no national guidelines to provide evidence-based recommendations on lipid testing and reporting for UK laboratories and clinicians. Here we present consensus guidance, following a review of published evidence by a multidisciplinary group of UK experts across a range of laboratory and clinical services. Recommendations include: the composition of a standard lipid profile; indications for, and composition of, an enhanced lipid profile including apolipoprotein B and lipoprotein (a); use of the Sampson-NIH calculation for LDL-c estimation; and guidance on when to flag abnormal results. This consensus guidance on lipid testing and reporting in the UK has been endorsed by HEART UK and The Association for Laboratory Medicine.

Item Type: Article
Additional Information: This is the Accepted Version accepted for publication in Annals of Clinical Biochemistry.
Uncontrolled Keywords: 1101 Medical Biochemistry and Metabolomics; 1103 Clinical Sciences; General Clinical Medicine
Subjects: Q Science > QH Natural history > QH301 Biology
R Medicine > R Medicine (General)
Divisions: Pharmacy and Biomolecular Sciences
Publisher: SAGE Publications
SWORD Depositor: A Symplectic
Date Deposited: 14 Jan 2025 13:31
Last Modified: 14 Jan 2025 13:31
DOI or ID number: 10.1177/00045632251315303
URI: https://researchonline.ljmu.ac.uk/id/eprint/25267
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