Article

Achar, J, Firman, JW, Cronin, MTD and Öberg, G (2024) A framework for categorizing sources of uncertainty in in silico toxicology methods: considerations for chemical toxicity predictions. Regulatory Toxicology and Pharmacology, 154. ISSN 0273-2300

Achar, J, Firman, JW, Tran, C, Kim, D, Cronin, MTD and Öberg, G (2024) Analysis of implicit and explicit uncertainties in QSAR prediction of chemical toxicity: A case study of neurotoxicity. Regulatory Toxicology and Pharmacology, 154. p. 105716. ISSN 0273-2300

Enoch, SJ, Hasarova, Z, Cronin, MTD, Bridgwood, K, Rao, S, Kluxen, FM and Frericks, M (2024) Metabolism-based category formation for the prioritisation of genotoxicity hazard assessment for plant protection product residues (Part 4): α-Chloroacetamides. Regulatory Toxicology and Pharmacology, 150. ISSN 0273-2300

Achar, J, Cronin, MTD, Firman, JW and Öberg, G (2024) A problem formulation framework for the application of in silico toxicology methods in chemical risk assessment. Archives of Toxicology. ISSN 0340-5761

Barnes, D, Firman, JW, Belfield, SJ, Cronin, MTD, Vinken, M, Janssem, M and Masereeuw, R (2024) Development of an adverse outcome pathway network for nephrotoxicity. Archives of Toxicology. ISSN 0340-5761

Yang, C, Rathman, JF, Ribeiro, V, Batke, M, Escher, SE, Firman, JW, Hobocienski, B, Kellner, R, Mostrag, A, Przybylak, KR and Cronin, MTD (2023) Update of the Cancer Potency Database (CPDB) to enable derivations of Thresholds Of Toxicological Concern (TTC) for cancer potency. Food and Chemical Toxicology, 182. ISSN 0278-6915

Botham, P, Cronin, MTD, Currie, R, Doe, J, Funk-Weyer, D, Gant, TW, Leist, M, Marty, S, van Ravenzwaay, B and Westmoreland, C (2023) Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology. Archives of Toxicology, 97 (12). pp. 3075-3083. ISSN 0340-5761

Cronin, MTD, Ball, N, Beken, S, Bender, H, Bercaru, O, Caneva, L, Corvaro, M, Currie, RA, Dawson, JL, Desert, P, Escher, SE, Franco, A, Irizar, A, Mehta, JM, Rogiers, V, Tremblay, RT, Westmoreland, C and Maxwell, G (2023) Exposure considerations in human safety assessment: Report from an EPAA Partners’ Forum. Regulatory Toxicology and Pharmacology, 144. ISSN 0273-2300

Enoch, SJ, Hasarova, Z, Cronin, MTD, Bridgwood, K, Rao, S, Kluxen, FM and Frericks, M (2023) Metabolism-based category formation for the prioritisation of genotoxicity hazard assessment for plant protection product residues (part III): Strobilurins. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Suciu, I, Pamies, D, Peruzzo, R, Wirtz, PH, Smirnova, L, Pallocca, G, Hauck, C, Cronin, MTD, Hengstler, JG, Brunner, T, Hartung, T, Amelio, I and Leist, M (2023) G × E interactions as a basis for toxicological uncertainty. Archives of Toxicology. ISSN 0340-5761

Belfield, SJ, Cronin, MTD, Enoch, SJ and Firman, JW (2023) Guidance for good practice in the application of machine learning in development of toxicological quantitative structure-activity relationships (QSARs). PLOS ONE, 18 (5).

Escher, S, Felter, SP, Hollnagel, H, Boobis, AR, Yang, C, Rathman, J, Cronin, MTD and Batke, M (2023) Workshop report on the evaluation of the updated and expanded carcinogen database to support derivation of threshold of toxicological concern values for DNA reactive carcinogens. ALTEX, 40 (2). ISSN 1868-596X

Firman, JW, Ebbrell, DJ, Bauer, FJ, Sapounidou, M, Hodges, G, Campos, B, Roberts, J, Gutsell, S, Thomas, PC, Bonnell, M and Cronin, MTD (2022) Construction of an In Silico Structural Profiling Tool Facilitating Mechanistically Grounded Classification of Aquatic Toxicants. Environmental Science and Technology. ISSN 0013-936X

Belfield, SJ, Firman, JW, Enoch, SJ, Madden, JC, Erik Tollefsen, K and Cronin, MTD (2022) A Review of Quantitative Structure-Activity Relationship Modelling Approaches to Predict the Toxicity of Mixtures. Computational Toxicology. p. 100251. ISSN 2468-1113

Cronin, MTD, Bauer, FJ, Bonnell, M, Campos, B, Ebbrell, DJ, Firman, JW, Gutsell, S, Hodges, G, Patlewicz, G, Sapounidou, M, Spinu, N, Thomas, PC and Worth, AP (2022) A scheme to evaluate structural alerts to predict toxicity – Assessing confidence by characterising uncertainties. Regulatory Toxicology and Pharmacology, 135. ISSN 0273-2300

Westmoreland, C, Bender, HJ, Doe, JE, Jacobs, MN, Kass, GEN, Madia, F, Mahony, C, Manou, I, Maxwell, G, Prieto, P, Roggeband, R, Sobanski, T, Schütte, K, Worth, AP, Zvonar, Z and Cronin, MTD (2022) Use of New Approach Methodologies (NAMs) in regulatory decisions for chemical safety: Report from an EPAA Deep Dive Workshop. Regulatory Toxicology and Pharmacology, 135. p. 105261. ISSN 0273-2300

Enoch, SJ, Hasarova, Z, Cronin, MTD and Frericks, M (2022) Sub-structure-based category formation for the prioritisation of genotoxicity hazard assessment for pesticide residues (part 2): Triazoles. Regulatory Toxicology and Pharmacology, 134. ISSN 0273-2300

Brockmeier, EK, Basili, D, Herbert, J, Rendal, C, Boakes, L, Grauslys, A, Taylor, NS, Danby, EB, Gutsell, S, Kanda, R, Cronin, MTD, Barclay, J, Antczak, P, Viant, MR, Hodges, G and Falciani, F (2022) Data-driven learning of narcosis mode of action identifies a CNS transcriptional signature shared between whole organism Caenorhabditis elegans and a fish gill cell line. Science of The Total Environment, 849. ISSN 0048-9697

Zwickl, C and Cronin, MTD (2022) Principles and Procedures for Assessment of Acute Toxicity Incorporating In Silico Methods. Computational Toxicology, 24. ISSN 2468-1113

Ouédraogo, G, Alexander-White, C, Bury, D, Clewell, HJ, Cronin, MTD, Cull, T, Dent, M, Desprez, B, Detroyer, A, Ellison, C, Giammanco, S, Hack, E, Hewitt, NJ, Kenna, G, Klaric, M, Kreiling, R, Lester, C, Mahony, C, Mombelli, E, Naciff, J et al, O'Brien, J, Schepky, A, Tozer, S, van der Burg, B, van Vugt, B, Stuard, S and Cosmetics Europe, (2022) Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment – A case study with parabens. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Gadaleta, D, Spinu, N, Roncaglioni, A, Cronin, MTD and Benfenati, E (2022) Prediction Of The Neurotoxic Potential Of Chemicals Based On Modelling Of Molecular Initiating Events Upstream Of The Adverse Outcome Pathways Of (Developmental) Neurotoxicity. International Journal of Molecular Sciences, 23. ISSN 1422-0067

Pestana, C, Enoch, SJ, Firman, JW, Madden, JC, Spinu, N and Cronin, MTD (2022) A Strategy to Define Applicability Domains for Read-Across. Computational Toxicology, 22. ISSN 2468-1113

Ball, N, Bars, R, Botham, P, Cuciureanu, A, Cronin, MTD, Doe, JE, Dudzina, T, Gant, T, Leist, M and van Ravenzwaay, B (2022) A Framework for Chemical Safety Assessment Incorporating New Approach Methodologies Within REACH. Archives of Toxicology. ISSN 0340-5761

Firman, JW, Cronin, MTD, Rowe, P, Semenova, E and Doe, JE (2022) The use of Bayesian methodology in the development and validation of a tiered assessment approach towards prediction of rat acute oral toxicity. Archives of Toxicology. ISSN 0340-5761

Enoch, SJ, Hasarova, Z, Cronin, MTD, Bridgwood, K, Rao, S, Kluxen, F and Frericks, M (2022) Sub-structure-based category formation for the prioritisation of genotoxicity hazard assessment for pesticide residues: Sulphonyl ureas. Regulatory Toxicology and Pharmacology, 129. ISSN 0273-2300

Cronin, MTD, Enoch, SJ, Madden, JC, Rathman, JF, Richarz, AN and Yang, C (2022) A Review of In Silico Toxicology Approaches to Support the Safety Assessment of Cosmetics-Related Materials. Computational Toxicology, 21. ISSN 2468-1113

Alexander-White, C, Bury, D, Cronin, MTD, Dent, M, Hack, E, Hewitt, NJ, Kenna, G, Naciff, J, Ouedraogo, G, Schepky, A, Mahony, C and Europe, C (2022) A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Spinu, N, Cronin, MTD, Lao, J, Bal-Price, A, Campia, I, Enoch, SJ, Madden, JC, Lagares, LM, Novič, M, Pamies, D, Scholz, S, Villeneuve, DL and Worth, A (2021) Probabilistic Modelling of Developmental Neurotoxicity based on a Simplified Adverse Outcome Pathway Network. Computational Toxicology, 21. ISSN 2468-1113

Spinu, N, Cronin, MTD, Madden, JC and Worth, A (2021) A Matter of Trust: Learning Lessons About Causality Will Make qAOPs Credible. Computational Toxicology, 21. ISSN 2468-1113

Johnson, C, Anger, LT, Benigni, R, Bower, D, Bringezu, F, Crofton, K, Cronin, MTD, Cross, KP, Dettwiler, M, Frericks, M, Melnikov, F, Miller, S, Roberts, DW, Suarez-Rodrigez, D, Roncaglioni, A, Lo Piparo, E, Tice, RR, Zwickl, C and Myatt, GJ (2021) Evaluating Confidence in Toxicity Assessments Based on Experimental Data and In Silico Predictions. Computational Toxicology, 21. ISSN 2468-1113

Bassan, A, Alves, VM, Amberg, A, Anger, LT, Beilke, L, Bender, A, Bernal, A, Cronin, MTD, Hsieh, JH, Johnson, C, Kemper, R, Mumtaz, M, Neilson, L, Pavan, M, Pointon, A, Pletz, J, Ruiz, P, Russo, DP, Sabnis, Y, Sandhu, R et al, Schaefer, M, Stavitskaya, L, Szabo, DT, Valentin, JP, Woolley, D, Zwickl, C and Myatt, GJ (2021) In silico approaches in organ toxicity hazard assessment: Current status and future needs for predicting heart, kidney and lung toxicities. Computational Toxicology, 20. ISSN 2468-1113

Bassan, A, Alves, VM, Amberg, A, Anger, LT, Auerbach, S, Beilke, L, Bender, A, Cronin, MTD, Cross, KP, Hsieh, J-H, Greene, N, Kemper, R, Kim, MT, Mumtaz, M, Noeske, T, Pavan, M, Pletz, J, Russo, DP, Sabnis, Y, Schaefer, M et al, Szabo, DT, Valentin, J-P, Wichard, J, Williams, D, Woolley, D, Zwickl, C and Myatt, GJ (2021) In silico approaches in organ toxicity hazard assessment: current status and future needs in predicting liver toxicity. Computational Toxicology. ISSN 2468-1113

Arnesdotter, E, Spinu, N, Firman, JW, Ebbrell, DJ, Cronin, MTD, Vanhaecke, T and Vinken, M (2021) Derivation, characterisation and analysis of an adverse outcome pathway network for human hepatotoxicity. Toxicology. ISSN 0300-483X

Batke, M, Afrapoli, FM, Kellner, R, Rathman, J, Yang, C, Cronin, MTD and Escher, S (2021) Threshold of Toxicological Concern - an update for non-genotoxic carcinogens. Frontiers in Toxicology. ISSN 2673-3080

Yang, C, Cronin, MTD, Arvidson, K, Bienfait, B, Enoch, SJ, Heldreth, B, Hobocienski, B, Muldoon-Jacobs, K, Lan, Y, Madden, JC, Magdziarz, T, Marusczyk, J, Mostrag, A, Nelms, MD, Przybylak, KR, Rathman, JF, Richarz, A-N, Richard, AM, Ribeiro, JV, Sacher, O et al, Schwab, C, Vitcheva, P, Volarath, P and Worth, AP (2021) COSMOS Next Generation – a public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals. Computational Toxicology, 19. ISSN 2468-1113

Pletz, J, Allen, T, Madden, JC, Cronin, MTD and Webb, SD (2021) A Mechanistic Model to Study the Kinetics and Toxicity of Salicylic Acid in the Kidney of Four Virtual Individuals. Computational Toxicology, 19. ISSN 2468-1113

Belfield, SJ, Enoch, SJ, Firman, JW, Madden, JC, Schultz, TW and Cronin, MTD (2021) Determination of “Fitness-for-Purpose” of Quantitative Structure-Activity Relationship (QSAR) Models to Predict (Eco-)Toxicological Endpoints for Regulatory Use. Regulatory Toxicology and Pharmacology, 123. ISSN 0273-2300

Bury, D, Alexander-White, C, Clewell, H, Cronin, MTD, Desprez, B, Detroyer, A, Efremenko, A, Firman, JW, Hack, E, Hewitt, NJ, Kenna, G, Klaric, M, Lester, C, Mahoney, C, Ouédraogo, G, Paini, A and Schepky, A (2021) New Framework for a Non-Animal Approach Adequately Assures the Safety of Cosmetic Ingredients – A Case Study on Caffeine. Regulatory Toxicology and Pharmacology, 123. ISSN 0273-2300

Sapounidou, M, Ebbrell, DJ, Bonnell, M, Campos, B, Firman, J, Gitsell, S and Cronin, MTD (2021) Development of an Enhanced Mechanistically-Driven Mode of Action Classification Scheme for Adverse Effects in Environmental Species. Environmental Science and Technology, 55 (3). pp. 1897-1907. ISSN 0013-936X

Pestana, C, Firman, JW and Cronin, MTD (2020) Incorporating Lines of Evidence from New Approach Methodologies (NAMs) to Reduce Uncertainties in a Category Based Read-Across: A Case Study for Repeated Dose Toxicity. Regulatory Toxicology and Pharmacology, 120. ISSN 0273-2300

Firman, JW, Pestana, CB, Rathman, JF, Vinken, M, Yang, C and Cronin, MTD (2020) A robust, mechanistically-based in silico structural profiler for hepatic cholestasis. Chemical Research in Toxicology, 34 (2). pp. 641-655. ISSN 0893-228X

Firman, JW, Punt, A, Cronin, MTD, Boobis, AR, Wilks, MF, Hepburn, PA, Thief, A and Fussell, KC (2020) Exploring the Potential of ToxCast Data in Supporting Read-across for Evaluation of Food Chemical Safety. Chemical Research in Toxicology, 34 (2). pp. 300-312. ISSN 0893-228X

Madden, JC, Enoch, SJ, Paini, A and Cronin, MTD (2020) A Review of In Silico Tools as Alternatives to Animal Testing: Principles, Resources and Applications. Alternatives to Laboratory Animals. ISSN 0261-1929

Masinja, W, Elliott, C, Modi, S, Enoch, SJ, Cronin, MTD, McInnes, EF and Currie, RA (2020) Comparison of the predictive nature of the genomic allergen rapid detection (GARD) assay with mammalian assays in determining the skin sensitisation potential of agrochemical active ingredients. Toxicology In Vitro. ISSN 0887-2333

Brozek, JL, Canelo-Aybar, C, Akl, EA, Bowen, JM, Bucher, J, Chiu, WA, Cronin, MTD, Djulbegovic, B, Falavigna, M, Guyatt, GH, Gordon, AA, Boon, MH, Hutubessy, RCW, Joore, MA, Katikireddi, V, LaKind, J, Langendam, M, Manja, V, Magnuson, K, Mathioudakis, AG et al, Meerpohl, J, Mertz, D, Mezencev, R, Morgan, R, Morgano, GP, Mustafa, R, O'Flaherty, M, Patlewicz, G, Riva, JJ, Posso, M, Rooney, A, Schlosser, PM, Schwartz, L, Shemilt, I, Tarride, J-E, Thayer, KA, Tsaioun, K, Vale, L, Wambaugh, J, Wignall, J, Williams, A, Xie, F, Zhang, Y, Schünemann, HJ and GRADE Working Group, (2020) GRADE Guidelines 30: The GRADE Approach to Assessing the Certainty of Modelled Evidence - an Overview in the Context of Health Decision-making. Journal of Clinical Epidemiology. ISSN 0895-4356

Johnson, C, Ahlberg, E, Anger, LT, Beilke, L, Benigni, R, Bercu, J, Bobst, S, Bower, D, Brigo, A, Campbell, S, Cronin, MTD, Crooks, I, Cross, CP, Doktorova, T, Exner, T, Faulkner, D, Fearon, IM, Fehr, M, Gad, SC, Gervais, V et al, Giddings, A, Glowienke, S, Hardy, B, Hasselgren, C, Hillegass, J, Jolly, R, Krupp, E, Lomnitski, L, Magby, J, Mestres, J, Milchak, L, Miller, S, Muster, W, Neilson, L, Parakhia, R, Parenty, A, Parris, P, Paulino, A, Paulino, AT, Roberts, DW, Schlecker, H, Stidl, R, Suarez-Rodrigez, D, Szabo, DT, Tice, RR, Urbisch, D, Vuorinen, A, Wall, B, Weiler, T, White, AT, Whritenour, J, Wichard, J, Woolley, D, Zwickl, C and Myatt, GJ (2020) Skin sensitization in silico protocol. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Mellor, CL, Tollefsen, K-E, LaLone, C, Cronin, MTD and Firman, JW (2020) In silico identification of chemicals capable of binding to the ecdysone receptor. Environmental Toxicology and Chemistry, 39 (7). pp. 1438-1450. ISSN 0730-7268

Spinu, N, Cronin, MTD, Enoch, SJ, Madden, JC and Worth, A (2020) Quantitative Adverse Outcome Pathway (qAOP) models for toxicity prediction. Archives of Toxicology, 94. pp. 1497-1510. ISSN 0340-5761

Rovida, C, Barton-Maclaren, T, Benfenati, E, Cronin, MTD, Caloni, F, Chandrasekera, C, Chesne, C, de Knecht, J, Dietrich, DR, Escher, SE, Fitzpatrick, S, Flannery, B, Herzler, M, Hougaard Bennekou, S, Hubesch, B, Kamp, H, Kisitu, J, Kleinstreuer, N, Kovarich, S, Leist, M et al, Maertens, A, Nugent, K, Pallocca, G, Pastor, M, Patlewicz, G, Pavana, M, Presgrave, O, Smirnova, L, Schwarz, M, Yamada, T and Hartung, T (2020) Internationalizationof Read-Across as a Validated New Approach Method (NAM) for Regulatory Toxicology. ALTEX : Alternativen zu Tierexperimenten, 37 (4). ISSN 0946-7785

Mahony, C, Ashton, R, Birk, B, Boobis, A and Cronin, MTD (2020) New Ideas for Non-Animal Approaches to Predict Repeated-Dose Systemic Toxicity: Report from an EPAA Blue Sky Workshop. Regulatory Toxicology and Pharmacology, 114. ISSN 0273-2300

Soares, S, Souza, LCR, Cronin, MTD, Waaga-Gasser, AM, Grossi, MF, Franco, GR and Tagliati, CA (2020) Biomarkers and in vitro strategies for nephrotoxicity and renal disease assessment. Journal of Nephrology and Renal Diseases, 5 (1). ISSN 2399-908X

Rogiers, V, Benfenati, E, Bernauer, U, Bodin, L and Cronin, MTD (2020) The way forward for assessing the human health safety of cosmetics in the EU - Workshop Proceedings. Toxicology, 436. ISSN 0300-483X

Punt, A, Firman, J, Boobis, A, Cronin, MTD, Gosling, JP, Wilks, MF, Hepburn, PA, Thiel, A and Fussell, K (2020) Potential of ToxCast data in the safety assessment of food chemicals. Toxicological Sciences. ISSN 1096-6080

Béquignon, OJM, Pawar, G, van de Water, B, Cronin, MTD and van Westen, GJP (2019) Computational Approaches for Drug-Induced Liver Injury (DILI) Prediction: State of the Art and Challenges. Reference Module in Biomedical Sciences.

Ebbrell, DJ, Madden, JC, Cronin, MTD, Schultz, T and Enoch, SJ (2019) Development of a fragment-based in silico profiler for SN2 thiol reactivity and its application in predicting toxicity of chemicals towards Tetrahymena pyriformis. Computational Toxicology, 13. ISSN 2468-1113

Drakvik, E, Altenburger, R, Aoki, Y, Backhaus, T, Bahadori, T, Barouki, R, Brack, W, Cronin, MTD, Demeniex, B, Hougaard Bennekou, S, van Klaveren, J, Kneuer, C, Kolossa Gehring, M, Lebret, E, Posthuma, L, Reiber, L, Rider, C, Ruegg, J, Testa, G, van der Burg, B et al, van der Voet, H, Warhurst, AM, van de Water, B, Yamazaki, K, Oberg, M and Bergman, A (2019) Statement on Advancing the Assessment of Chemical Mixtures and their Risks for Human Health and the Environment. Environment International, 134. ISSN 0160-4120

Laroche, C, Annys, E, Bender, H, Botelho, D, Botham, P, Brendler-Schwaab, S, Clayton, R, Corvaro, M, Dal Negro, G, Delannois, F, Dent, M, Desaintes, C, Desprez, B, Dhalluin, S, Hartmann, A, Hoffmann-Doerr, S, Hubesch, B, Irizar, A, Manou, I, Müller, BP et al, Nadzialek, S, Prieto, P, Rasenberg, M, Roggeband, R, Rowan, TG, Schutte, K, van de Water, B, Westmoreland, C, Whelan, M, Wilschut, A, Zvonimir, Z and Cronin, MTD (2019) Finding synergies for the 3Rs – Repeated dose toxicity testing: Report from an EPAA partners' forum. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Spinu, N, Bal-Price, A, Cronin, MTD, Enoch, SJ, Madden, JC and Worth, A (2019) Development and Analysis of an Adverse Outcome Pathway Network for Human Neurotoxicity. Archives of Toxicology, 93 (10). pp. 2759-2772. ISSN 0340-5761

Hasselgren, C, Ahlberg, E, Akahori, Y, Amberg, A, Anger, L, Atienzar, F, Auerbach, S, Beilke, L, Bellion, P, Benigni, R, Bercu, J, Booth, E, Bower, D, Brigo, A, Cammerer, Z, Cronin, MTD, Crooks, I, Cross, K, Custer, L, Dobo, K et al, Doktorova, TY, Faulkner, D, Ford, DA, Fortin, MC, Frericks, M, Gad-McDonald, SE, Gellatly, N, Gerets, H, Gervais, V, Glowienke, S, van Gompel, J, Harvey, JS, Hillegass, J, Honma, M, Hsieh, JH, Hsu, CW, Barton-Maclaren, TS, Johnson, C, Jolly, R, Jones, D, Kemper, R, Kenyon, MO, Kruhlak, NL, Kulkarni, SA, Kümmerer, K, Leavitt, P, Maston, S, Miller, S, Moudgal, C, Muster, W, Paulino, A, Piparo, EL, Powley, M, Quigley, DP, Reddy, MV, Richarz, AN, Schilter, B, Snyder, RD, Stavitskaya, L, Stidl, R, Szabo, DT, Teasdale, A, Tice, RR, Trejo-Martin, A, Vuorinen, A, Wall, BA, Watts, P, White, AT, Wichard, J, Witt, KL, Woolley, A, Woolley, D, Zwickl, C and Myatt, GJ (2019) Genetic toxicology in silico protocol. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Pawar, G, Madden, JC, Ebbrell, DJ, Firman, JW and Cronin, MTD (2019) In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR. Frontiers in Pharmacology, 10. ISSN 1663-9812

Cronin, MTD, Richarz, A-N and Schultz, T (2019) Identification and Description of the Uncertainty, Variability, Bias and Influence in Quantitative Structure-Activity Relationships (QSARs) for Toxicity Prediction. Regulatory Toxicology and Pharmacology, 106. pp. 90-104. ISSN 0273-2300

Desprez, B, Birk, B, Blaauboer, B, Boobis, A, Carmichael, P, Cronin, MTD, Curie, R, Daston, G, Hubesch, B, Jennings, P, Klaric, M, Kroese, D, Mahony, C, Ouédraogo, G, Piersma, A, Richarz, A-N, Schwarz, M, van Benthem, J, van de Water, B and Vinken, M (2019) A mode-of-action ontology model for safety evaluation of chemicals: outcome of a series of workshops on repeated dose toxicity. Toxicology In Vitro. pp. 44-50. ISSN 0887-2333

Madden, JC, Pawar, G, Cronin, MTD, Webb, SD, Tan, Y-M and Paini, A (2019) In Silico Resources to Assist in the Development and Evaluation of Physiologically-Based Kinetic Models. Computational Toxicology, 11. pp. 33-49. ISSN 2468-1113

Firman, JW, Belfield, SJ, Chen, G, Jackson, M, Lam, FH, Richmond, C, Smith, J, Steinmetz, FP and Cronin, MTD (2019) Chemoinformatic Consideration of Novel Psychoactive Substances: Compilation and Preliminary Analysis of a Categorised Dataset. Molecular Informatics, 38 (8-9). ISSN 1611-0218

Ellison, C, Blackburn, K, Carmichael, P, Clewell, H, Cronin, MTD, Desprez, B, Escher, S, Ferguson, S, Grégoire, S, Hewitt, N, Hollnagel, H, Klaric, M, Patel, A, Salhi, S, Schepky, A, Schmitt, B, Wambaugh, J and Worth, A (2019) Challenges in working towards an internal Threshold of Toxicological Concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Diukendjieva, A, Tsakovska, I, Alov, P, Pencheva, T, Pajeva, I, Worth, A, Madden, J and Cronin, MTD (2018) Advances in the Prediction of Gastrointestinal Absorption: Quantitative Structure-Activity Relationship (QSAR) modelling of PAMPA Permeability. Computational Toxicology, 10. pp. 51-59. ISSN 2468-1113

Beilmann, M, Boonen, H, Czich, A, Dear, G, Hewitt, P, Mow, T, Newham, P, Oinonen, T, Pognan, F, Roth, A, Valentin, J-P, Van Goethem, F, Weaver, RJ, Birk, B, Boyer, S, Caloni, F, Chen, AE, Corvi, R, Cronin, MTD, Daneshian, M et al, Ewart, LC, Fitzgerald, RE, Hamilton, GA, Hartung, T, Kangas, JD, Kramer, NI, Leist, M, Marx, U, Polak, S, Rovida, C, Testai, E, Van der Water, B, Vulto, P and Steger-Hartmann, T (2018) Optimizing drug discovery by Investigative Toxicology: Current and future trends. Altex-Alternatives to Animal Experimentation. ISSN 1868-596X

Cronin, MTD, Madden, JC, Yang, C and Worth, A (2018) Unlocking the Potential of In Silico Chemical Safety Assessment – A Report on a Cross-Sector Symposium on Current Opportunities and Future Challenges. Computational Toxicology, 10. pp. 38-43. ISSN 2468-1113

Mellor, CL, Marchese Robinson, RL, Benigni, R, Ebbrell, DJ, Enoch, SJ, Firman, JW, Madden, JC, Pawar, G, Yang, C and Cronin, MTD (2018) Molecular Fingerprint-Derived Similarity Measures for Toxicological Read-Across: Recommendations for Optimal Use. Regulatory Toxicology and Pharmacology, 101. pp. 121-134. ISSN 0273-2300

Schultz, TW, Richarz, A-N and Cronin, MTD (2018) Assessing Uncertainty in Read-Across: Questions to Evaluate Toxicity Predictions Based on Knowledge Gained from Case Studies. Computational Toxicology. ISSN 2468-1113

Pletz, J, Enoch, SJ, Jais, DM, Mellor, CL, Pawar, G, Madden, JC, Webb, SD, Tagliati, C and Cronin, MTD (2018) A Critical Review of Adverse Effects to the Kidney: Mechanisms, Data Sources and In Silico Tools to Assist Prediction. Expert Opinion on Drug Metabolism and Toxicology. ISSN 1744-7607

Matveieva, M, Cronin, MTD and Polishchuk, P (2018) Interpretation of QSAR Models: Mining Structural Patterns Taking into Account Molecular Context. Molecular Informatics. ISSN 1868-1743

Diukendjieva, A, Alov, P, Pencheva, T, Tsakovska, I, Richarz, A, Kren, V, Cronin, MTD and Pajeva, I (2018) In vitro and in silico studies of the membrane permeability of natural flavonoids from Silybum marianum (L.) Gaertn. and their derivatives. Phytomedicine, 53. pp. 79-85. ISSN 0944-7113

Nelms, M, Mellor, C, Enoch, SJ, Judson, R, Patlewicz, G, Richard, A, Madden, JC, Cronin, MTD and Edwards, S (2018) A Mechanistic Framework for Integrating Chemical Structure and High-Throughput Screening Results to Improve Toxicity Predictions. Computational Toxicology, 8. ISSN 2468-1113

Firman, J, Patel, A, Date, M, Cronin, MTD and Schultz, TW (2018) Read-across of 90-day rodent repeated-dose toxicity: A case study for selected simple aryl alcohol alkyl carboxylic acid esters. Computational Toxicology, 7. pp. 1-8. ISSN 2468-1113

Myatt, GJ, Ahlberg, E, Akahori, E, Allen, D, Amberg, A, Anger, LT, Aptula, A, Auerbach, S, Beilke, L, Bellion, P, Benigni,, R, Bercu, J, Booth, ED, Bower, D, Brigo, A, Burden, N, Cammerer, Z, Cronin, MTD, Cross, KP, Custer, L et al, Dettwiler, M, Dobo, K, Ford, KA, Fortin, MC, Gad-McDonald, SE, Gellatly, N, Gervais, V, Glover, KP, Glowienke, S, van Gompel, J, Gutsell, S, Hardy, B, Harvey, JS, Hillegass, J, Honma, M, Hsieh, JH, Hsu, CW, Hughes, K, Johnson, C, Jolly, R, Jones, D, Kemper, R, Kenyon, MO, Kim, MT, Kruhlak, NL, Kulkarni, SA, Kümmerer, K, Leavitt, P, Majer, B, Masten, S, Miller, S, Moser, J, Mumtaz, M, Muster, W, Neilson, L, Oprea, TI, Patlewicz, G, Paulino, A, Piparo, EL, Powley, M, Quigley, DP, Reddy, MV, Richarz, AN, Ruiz, P, Schilter, B, Serafimova, R, Simpson, W, Stavitskaya, L, Stidl, R, Suarez-Rodriguez, D, Szabo, DT, Teasdale, A, Trejo-Martin, A, Valentin, JP, Vuorinen, A, Wall, BA, Watts, P, White, AT, Wichard, J, Witt, KL, Woolley, A, Woolley, D, Zwickl, C and Hasselgren, C (2018) In silico toxicology protocols. Regulatory Toxicology and Pharmacology. ISSN 0273-2300

Patlewicz, G, Cronin, MTD, Helman, G, Lambert, JC, Lizarraga, LE and Shah, I (2018) Navigating through the minefield of read-across frameworks: A commentary perspective. Computational Toxicology. ISSN 2468-1113

Patel, M, Chilton, M, Sartini, A, Gibson, L, Barber, C, Covey-Crump, L, Przybylak, KR, Cronin, MTD and Madden, JC (2018) Assessment and Reproducibility of Quantitative Structure-Activity Relationship Models by the Nonexpert. Journal of Chemical Information and Modeling, 58 (3). pp. 673-682. ISSN 1549-9596

Li, J, Zhang, X, Yang, Y, Huang, T, Li, C, Su, M, Cronin, MTD and Zhao, Y (2017) Development of thresholds of excess toxicity for environmental species and their application to identification of modes of acute toxic action. Science of the Total Environment, 616. pp. 491-499. ISSN 0048-9697

Cronin, MTD and Richarz, A (2017) Relationship Between Adverse Outcome Pathways and Chemistry-Based in Silico Models to Predict Toxicity. Applied In Vitro Toxicology, 3 (4). pp. 286-297. ISSN 2332-1512

Sanz, F, Pognan, F, Steger-Hartmann, T, Diaz, C, Cases, M, Pastor`, M, Marc, P, Wichard, J, Briggs, K, Watson, D, Kleinöder,, T, Yang, C, Amberg, A, Beaumont, M, Brookes, AJ, Brunak, S, Cronin, MTD, Ecker, GF, Escher, S, Greene, N et al, Guzman, A, Hersey, A, Jacques, P, Lammens, L, Mestres, J, Muster, W, Northeved, H, Pinches, M, Saiz, J, Sajot, N, Valencia, A, van der Lei, J, Vermeulen, NPE, Vock, E, Wolber, G and Zamora, I (2017) Legacy data sharing to improve drug safety assessment: the eTOX project. Nature Reviews Drug Discovery, 16. pp. 811-812. ISSN 1474-1776

Puzyn, T, Jeliazkova, N, Sarimveis, H, Marchese Robinson, RL, Lobaskin, V, Rallo, R, Richarz, AN, Gajewicz, A, Papadopulos, MG, Hastings, J, Cronin, MTD, Benfenati, E and Fernandez, A (2017) Perspectives from the NanoSafety Modelling Cluster on the validation criteria for (Q)SAR models used in nanotechnology. Food and Chemical Toxicology. ISSN 0278-6915

Yang, C, Barlow, SM, Muldoon Jacobs, KL, Vitcheva, V, Boobis, AR, Felter, SP, Arvidson, KB, Keller, D, Cronin, MTD, Enoch, SJ, Worth, A and Hollnagel, HM (2017) Thresholds of Toxicological Concern for Cosmetics-Related Substances: New Database, Thresholds, and Enrichment of Chemical Space. Food and Chemical Toxicology, 109 (Part 1). pp. 170-193. ISSN 0278-6915

Cronin, MTD, Enoch, SJ, Mellor, CL, Przybylak, KR, Richarz, AN and Madden, JC (2017) In Silico Prediction of Organ Level Toxicity: Linking Chemistry to Adverse Effects. Toxicological Research, 33 (3). pp. 173-182. ISSN 1976-8257

Madden, JC, Webb, SD, Enoch, SJ, Colley, H, Murdoch, C, Shipley, R, Sharma, P, Yang, C and Cronin, MTD (2017) In silico prediction of skin metabolism and its implication in toxicity assessment. Computational Toxicology. ISSN 2468-1113

Schultz, TW and Cronin, MTD (2017) Lessons Learned from Read-Across Case Studies for Repeated-Dose Toxicity. Regulatory Toxicology and Pharmacology, 88. pp. 185-191. ISSN 0273-2300

Tsakovska, I, Pajeva, I, Al Sharif, M, Alov, P, Fioravanzo, E, Kovarich, S, Worth, AP, Richarz, A-N, Yang, C, Mostrag-Szlichtyng, A and Cronin, MTD (2017) Quantitative Structure - Skin permeability Relationships. Toxicology, 387. pp. 27-42. ISSN 0300-483X

Brockmeier, EK, Hodges, G, Hutchinson, TH, Butler, E, Hecker, M, Tollefsen, KE, Garcia-Reyero, N, Kille, P, Becker, D, Chipman, K, Colbourne, J, Collette, TW, Cossins, A, Cronin, MTD, Graystock, P, Gutsell, S, Knapen, D, Katsiadaki, I, Lange, A, Marshall, S et al, Owen, SF, Perkins, EJ, Plaistow, S, Schroeder, A, Taylor, D, Viant, M, Ankley, G and Falciani, F (2017) The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment. TOXICOLOGICAL SCIENCES, 158 (2). pp. 252-262. ISSN 1096-6080

Boobis, AR, Brown, P, Cronin, MTD, Edwards, J, Galli, CL, Goodman, J, Jacobs, A, Kirkland, D, Luijten, M, Marsaux, CFM, Martin, M, Yang, C and Hollnagel, HM (2017) Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their revaluation. Critical Reviews in Toxicology. ISSN 1547-6898

Schultz, TW, Przybylak, KR, Richarz, AN, Mellor, CL, Bradbury, SP and Cronin, MTD (2017) Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected 2-alkyl-1-alkanols. Computational Toxicology, 2. pp. 28-38. ISSN 2468-1113

Przybylak, KR, Madden, JC, Covey-Crump, E, Gibson, L, Barber, C, Patel, M and Cronin, MTD (2017) Characterisation of data resources for in silico modelling: benchmark datasets for ADME properties. Expert Opinion on Drug Metabolism and Toxicology. ISSN 1744-7607

Mellor, CL, Schultz, TW, Przybylak, KR, Richarz, AN, Bradbury, SP and Cronin, MTD (2017) Read-Across for Rat Oral Gavage Repeated-Dose Toxicity for Short-Chain Mono-Alkylphenols: A Case Study. Computational Toxicology, 2. pp. 1-11. ISSN 2468-1113

Benito, JVS, Paini, A, Richarz, A-N, Meinl, T, Berthold, MR, Cronin, MTD and Worth, AP (2017) Automated workflows for modelling chemical fate, kinetics and toxicity. Toxicology In Vitro. ISSN 0887-2333

Schultz, TW, Przybylak, KR, Richarz, AN, Mellor, CL, Bradbury, SP and Cronin, MTD (2017) Read-across of 90-day rat oral repeated-dose toxicity: A case study for selected n-alkanols. Computational Toxicology. ISSN 2468-1113

Cronin, MTD (2017) (Q)SARs to Predict Environmental Toxicities: Current Status and Future Needs. Environmental Science: Processes and Impacts, 19 (3). pp. 213-220. ISSN 2050-7887

Ebbrell, DJ, Madden, JC, Cronin, MTD, Schultz, TW and Enoch, SJ (2017) Validation of a fragment-based profiler for thiol reactivity for the prediction of toxicity: skin sensitisation and tetrahymena pyriformis. Chemical Research in Toxicology, 30 (2). pp. 604-613. ISSN 0893-228X

Gajewicz, A, Jagiello, K, Cronin, MTD, Leszczynski, J and Puzyn, T (2016) Addressing a bottle neck for regulation of nanomaterials: quantitative read-across (Nano-QRA) algorithm for cases when only limited data is available. Environmental Science: Nano, 4 (2). pp. 346-358. ISSN 2051-8153

Lawson, MK, Cronin, MTD, Valko, M and Jomová, K (2016) Chelators in Iron and Copper Toxicity. Current Pharmacology Reports, 2 (6). pp. 271-280. ISSN 2198-641X

Cassano, A, Marchese Robinson, RL, Palczewska, A, Puzyn, T, Gajewicz, A, Tran, L, Manganelli, S and Cronin, MTD (2016) Comparing the CORAL and random forest approaches for modelling the in vitro cytotoxicity of silica nanomaterials. Alternatives to the Laboratory Animals, 44 (6). ISSN 0261-1929

Przybylak, KP, Schultz, TW, Richarz, AN, Mellor, CL, Escher, SE and Cronin, MTD (2016) Read-Across of 90-Day Rat Oral Repeated-Dose Toxicity: A Case Study for Selected β-olefinic Alcohols. Computational Toxicology. ISSN 2468-1113

Ebbrell, DJ, Madden, JC, Cronin, MTD, Schultz, TW and Enoch, SJ (2016) Development of a Fragment-Based in Silico Profiler for Michael Addition Thiol Reactivity. Chemical Research in Toxicology, 29 (6). pp. 1073-1081. ISSN 1520-5010

Ellison, CM, Piechota, P, Madden, JC, Enoch, SJ and Cronin, MTD (2016) Adverse Outcome Pathway (AOP) Informed Modeling of Aquatic Toxicology: QSARs, Read-Across, and Interspecies Verification of Modes of Action. Environmental Science & Technology, 50 (7). pp. 3995-4007. ISSN 1520-5851

Ball, N, Cronin, MTD, Shen, J, Blackburn, K, Booth, ED, Bouhifd, M, Donley, E, Egnash, L, Hastings, C, Juberg, DR, Kleensang, A, Kleinstreuer, N, Kroese, ED, Lee, AC, Luechtefeld, T, Maertens, A, Marty, S, Naciff, JM, Palmer, J, Pamies, D et al, Penman, M, Richarz, AN, Russo, DP, Stuard, SB, Patlewicz, G, van Ravenzwaay, B, Wu, S, Zhu, H and Hartung, T (2016) Toward Good Read-Across Practice (GRAP) guidance. ALTEX. ISSN 1868-8551

Al Sharif, M, Tsakovska, I, Pajeva, I, Alov, P, Fioravanzo, E, Bassan, A, Kovarich, S, Yang, C, Mostrag-Szlichtyng, A, Vitcheva, V, Worth, AP, Richarz, AN and Cronin, MTD (2016) The application of molecular modelling in the safety assessment of chemicals: A case study on ligand-dependent PPARγ dysregulation. Toxicology. ISSN 1879-3185

Mellor, CL, Steinmetz, FP and Cronin, MTD (2016) The identification of nuclear receptors associated with hepatic steatosis to develop and extend adverse outcome pathways. Critical Reviews in Toxicology, 46 (2). pp. 138-152. ISSN 1547-6898

Mellor, CL, Steinmetz, FP and Cronin, MTD (2016) Using Molecular Initiating Events to Develop a Structural Alert Based Screening Workflow for Nuclear Receptor Ligands Associated with Hepatic Steatosis. Chemical Research in Toxicology, 29 (2). pp. 203-212. ISSN 1520-5010

Berggren, E, Amcoff, P, Benigni, R, Blackburn, K, Carney, E, Cronin, MTD, Deluyker, H, Gautier, F, Judson, RS, Kass, GEN, Keller, D, Knight, D, Lilienblum, W, Mahony, C, Rusyn, I, Schultz, T, Schwarz, M, Schueuermann, G, White, A, Burton, J et al, Lostia, AM, Munn, S and Worth, A (2015) Chemical Safety Assessment Using Read-Across: Assessing the Use of Novel Testing Methods to Strengthen the Evidence Base for Decision Making. ENVIRONMENTAL HEALTH PERSPECTIVES, 123 (12). pp. 1232-1240. ISSN 0091-6765

Robinson, RLM, Cronin, MTD, Richarz, A-N and Rallo, R (2015) An ISA-TAB-Nano based data collection framework to support data-driven modelling of nanotoxicology. BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 6. pp. 1978-1999. ISSN 2190-4286

Antczak, P, White, TA, Giri, A, Michelangeli, F, Viant, MR, Cronin, MTD, Vulpe, C and Falciani, F (2015) Systems Biology Approach Reveals a Calcium-Dependent Mechanism for Basal Toxicity in Daphnia magna. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 49 (18). pp. 11132-11140. ISSN 0013-936X

Burden, N, Sewell, F, Andersen, ME, Boobis, A, Chipman, JK, Cronin, MTD, Hutchinson, TH, Kimber, I and Whelan, M (2015) Adverse Outcome Pathways can drive non-animal approaches for safety assessment. JOURNAL OF APPLIED TOXICOLOGY, 35 (9). pp. 971-975. ISSN 0260-437X

Steinmetz, FP, Madden, JC and Cronin, MTD (2015) Data quality in the human and environmental health sciences: Using statistical confidence scoring to improve QSAR/QSPR modeling. Journal of Chemical Information and Modeling, 55 (8). pp. 1739-1746. ISSN 1549-960X

Ellison, CM, Madden, JC, Cronin, MTD and Enoch, SJ (2015) Investigation of the Verhaar scheme for predicting acute aquatic toxicity: improving predictions obtained from Toxtree ver. 2.6. Chemosphere, 139. pp. 146-154. ISSN 1879-1298

Wen, Y, Su, L, Qin, W, Zhao, Y, Madden, JC, Steinmetz, FP and Cronin, MTD (2015) Investigation of Critical Body Residues and Modes of Toxic Action Based on Injection and Aquatic Exposure in Fish. WATER AIR AND SOIL POLLUTION, 226 (6). pp. 1-11. ISSN 0049-6979

Cronin, MTD, Schultz, TW, Amcoff, P, Berggren, E, Gautier, F, Klaric, M, Knight, DJ, Mahony, C, Schwarz, M and White, A (2015) A Strategy for Structuring and Reporting a Read-Across Prediction of Toxicity. Regulatory Toxicology and Pharmacology, 72 (3). pp. 586-601. ISSN 1096-0295

Nelms, MD, Ates, G, Madden, JC, Vinken, M, Cronin, MTD, Rogiers, V and Enoch, SJ (2015) Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes. ARCHIVES OF TOXICOLOGY, 89 (5). pp. 733-741. ISSN 0340-5761

Hewitt, M, Ellison, CM, Cronin, MTD, Madden, JC, Pastor, M, Steger-Hartmann, T, Munoz-Muriendas, J and Pognan, F (2015) Ensuring confidence in predictions: A scheme to assess the scientific validity of in silico models. Advanced Drug Delivery Reviews, 86. pp. 101-111. ISSN 0169-409X

Steinmetz, FP, Mellor, CL, Meinl, T and Cronin, MTD (2015) Screening Chemicals for Receptor-Mediated Toxicological and Pharmacological Endpoints: Using Public Data to Build Screening Tools within a KNIME Workflow. MOLECULAR INFORMATICS, 34 (2-3). pp. 171-178. ISSN 1868-1743

Richarz, A-N, Madden, JC, Marchese Robinson, RL, Lubiński, Ł, Mokshina, E, Urbaszek, P, Kuz׳min, VE, Puzyn, T and Cronin, MTD (2015) Development of computational models for the prediction of the toxicity of nanomaterials. Perspectives in Science, 3 (1-4). pp. 27-29. ISSN 2213-0209

Gajewicz, A, Cronin, MTD, Rasulev, B, Leszczynski, J and Puzyn, T (2015) Novel approach for efficient predictions properties of large pool of nanomaterials based on limited set of species: nano-read-across. NANOTECHNOLOGY, 26 (1). pp. 1-9. ISSN 0957-4484

Golbamaki, N, Rasulev, B, Cassano, A, Robinson, RLM, Benfenati, E, Leszczynski, J and Cronin, MTD (2015) Genotoxicity of metal oxide nanomaterials: review of recent data and discussion of possible mechanisms. NANOSCALE, 7 (6). pp. 2154-2198. ISSN 2040-3364

Gocht, T, Berggren, E, Ahr, HJ, Cotgreave, I, Cronin, MTD, Daston, G, Hardy, B, Heinzle, E, Hescheler, J, Knight, DJ, Mahony, C, Peschanski, M, Schwarz, M, Thomas, RS, Verfaillie, C, White, A and Whelan, M (2015) The SEURAT-1 Approach towards Animal Free Human Safety Assessment. Altex-Alternatives to Animal Experimentation, 32 (1). pp. 9-24. ISSN 1868-596X

Tollefsen, KE, Scholz, S, Cronin, MTD, Edwards, SW, de Knecht, J, Crofton, K, Garcia-Reyero, N, Hartung, T, Worth, A and Patlewicz, G (2014) Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA). REGULATORY TOXICOLOGY AND PHARMACOLOGY, 70 (3). pp. 629-640. ISSN 0273-2300

Enoch, SJ, Roberts, DW, Madden, JC and Cronin, MTD (2014) Development of an In Silico Profiler for Respiratory Sensitisation. Alternatives to the Laboratory Animals, 42 (6). pp. 367-375. ISSN 0261-1929

Rodriguez-Sanchez, N, Cronin, MTD, Lillicrap, A, Madden, JC, Piechota, P and Tollefsen, KE (2014) DEVELOPMENT OF A LIST OF REFERENCE CHEMICALS FOR EVALUATING ALTERNATIVE METHODS TO IN VIVO FISH BIOACCUMULATION TESTS. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 33 (12). ISSN 0730-7268

Eriksson, L, Jaworska, J, Worth, AP, Cronin, MTD, McDowell, RM and Gramatica, P (2003) Methods for reliability and uncertainty assessment and for applicability evaluations of classification- and regression-based QSARs. ENVIRONMENTAL HEALTH PERSPECTIVES, 111 (10). pp. 1361-1375. ISSN 0091-6765

Cronin, MTD, Walker, JD, Jaworska, JS, Comber, MHI, Watts, CD and Worth, AP (2003) Use of QSARs in international decision-making frameworks to predict ecologic effects and environmental fate of chemical substances. ENVIRONMENTAL HEALTH PERSPECTIVES, 111 (10). pp. 1376-1390. ISSN 0091-6765

Cronin, MTD, Jaworska, JS, Walker, JD, Comber, MHI, Watts, CD and Worth, AP (2003) Use of QSARs in international decision-making frameworks to predict health effects of chemical substances. ENVIRONMENTAL HEALTH PERSPECTIVES, 111 (10). pp. 1391-1401. ISSN 0091-6765

Thesis

Cronin, MTD (1990) Quantitative structure-activity relationships of comparative toxicity to aquatic organisms. Doctoral thesis, Liverpool Polytechnic.