Ehtezazi, T, Rahman, K, Davies, R and Leach, AG (2023) The Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer's Disease. Journal of Alzheimer's disease reports, 7 (1). pp. 173-211. ISSN 2542-4823

Washington, JB, Assante, M, Yan, C, McKinney, D, Juba, V, Leach, AG, Baillie, SE and Reid, M (2021) Trialkylammonium salt degradation: implications for methylation and cross-coupling. Chemical Science, 12 (20). pp. 6949-6963. ISSN 2041-6520

Islam, Y, Leach, AG, Smith, J, Pluchino, S, Coxon, CR, Sivakumaran, M, Downing, J, Fatokun, AA, Teixidò, M and Ehtezazi, T (2021) Physiological and Pathological Factors Affecting Drug Delivery to the Brain by Nanoparticles. Advanced Science. ISSN 2198-3844

Islam, Y, Ehtezazi, P, Cashmore, A, Marinsalda, E, Leach, AG, Coxon, CR, Fatokun, AA, Sexton, DW, Khan, I, Zouganelis, GD, Downing, J, Pluchino, S, Sivakumaran, M, Teixido, M and Ehtezazi, T (2020) The Inclusion of a Matrix Metalloproteinase-9 Responsive Sequence in Self-assembled Peptide-based Brain-Targeting Nanoparticles Improves the Efficiency of Nanoparticles Crossing the Blood-Brain Barrier at Elevated MMP-9 Levels. Journal of Pharmaceutical Sciences, 110 (3). pp. 1349-1364. ISSN 0022-3549

Islam, Y, Khalid, A, Pluchino, S, Sivakumaran, M, Teixidò, M, Leach, AG, Fatokun, AA, Downing, J, Coxon, CR and Ehtezazi, T (2020) Development of Brain Targeting Peptide Based MMP-9 Inhibiting Nanoparticles for the Treatment of Brain Diseases with Elevated MMP-9 Activity. Journal of Pharmaceutical Sciences, 109 (10). pp. 3134-3144. ISSN 0022-3549

Islam, Y, Leach, AG, Smith, J, Pluchino, S, Coxon, CR, Sivakumaran, M, Downing, J, Fatokun, AA, Teixidò, M and Ehtezazi, T (2020) Peptide based drug delivery systems to the brain. Nano Express. ISSN 2632-959X

Li, X, Payne, DT, Ampolu, B, Bland, N, Brown, JT, Dutton, MJ, Fitton, CA, Gulliver, A, Hale, L, Hamza, D, Jones, G, Lane, R, Leach, AG, Male, L, Merisor, EG, Morton, MJ, Quy, AS, Roberts, R, Scarll, R, Schulz-Utermoehl, T et al, Stankovic, T, Stevenson, B, Fossey, JS and Agathanggelou, A (2019) Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia. MedChemComm, 10 (8). pp. 1379-1390. ISSN 2040-2503

Higgs, PL, Ruiz-Sanchez, AJ, Dalmina, M, Horrocks, BR, Leach, AG and Fulton, DA (2019) Enhancing the kinetics of hydrazone exchange processes: an experimental and computational study. Organic & Biomolecular Chemistry. ISSN 1477-0520

Lukac, I, Abdelhakim, H, Ward, RA, St-Gallay, SA, Madden, JC and Leach, AG (2019) Predicting protein–ligand binding affinity and correcting crystal structures with quantum mechanical calculations: lactate dehydrogenase A. Chemical Science, 10 (7). pp. 2218-2227. ISSN 2041-6520

Verhoork, SJM, Jennings, CE, Rozatian, N, Reeks, J, Meng, J, Corlett, EK, Bunglawala, F, Noble, MEM, Leach, AG and Coxon, CR (2018) Tuning the binding affinity and selectivity of perfluoroaryl-stapled peptides by cysteine-editing. Chemistry - A European Journal, 25 (1). pp. 177-182. ISSN 0947-6539

Johnston, C, West, T, Dooley, R, Reid, M, Jones, AB, King, E, Leach, AG and Lloyd-Jones, GC (2018) Anion-Initiated Trifluoromethylation by TMSCF3: Deconvolution of the Siliconate-Carbanion Dichotomy by Stopped-Flow NMR/IR. Journal of the American Chemical Society. ISSN 0002-7863

Xu, C, Muir, CW, Leach, AG, Kennedy, AR and Watson, AJB (2018) Catalytic Enantioselective Synthesis of α-Chiral Azaheteroaryl Ethylamines by Asymmetric Protonation. Angewandte Chemie International Edition. ISSN 1521-3773

Yoshizawa, A, Feula, A, Leach, AG, Male, L and Fossey, JS (2018) Palladium and Platinum 2,4-cis-amino Azetidine and Related Complexes. Frontiers in Chemistry, 6. ISSN 2296-2646

Yoshizawa, A, Feula, A, Male, L, Leach, AG and Fossey, JS (2018) Rigid and concave, 2,4-cis-substituted azetidine derivatives: A platform for asymmetric catalysis. Scientific Reports, 8 (1). ISSN 2045-2322

Griffen, EJ, Dossetter, AG, Leach, AG and Montague, S (2018) Can we accelerate medicinal chemistry by augmenting the chemist with Big Data and artificial intelligence? Drug Discovery Today. ISSN 1359-6446

Davies, MJ, Leach, AG and Riley, F (2018) An Investigation into Drug Partitioning Behaviour in Simulated Pulmonary Surfactant Monolayers with Associated Molecular Modelling. Surface and Interface Analysis. ISSN 1096-9918

Ballard, A, Ahmad, HO, Narduolo, S, Rosa, L, Chand, N, Cosgrove, DA, Varkonyi, P, Asaad, N, Tomasi, S, Buurma, NJ and Leach, AG (2017) Quantitative Prediction of Rate Constants for Aqueous Racemization To Avoid Pointless Stereoselective Syntheses. Angewandte Chemie International Edition, 57 (4). pp. 982-985. ISSN 1521-3773

Lukac, I, Zarnecka, J, Griffen, EJ, Dossetter, AG, St-Gallay, SA, Enoch, SJ, Madden, JC and Leach, AG (2017) Turbocharging Matched Molecular Pair Analysis: Optimizing the Identification and Analysis of Pairs. Journal of Chemical Information Modeling. ISSN 1549-9596

Kramer, C, Ting, A, Zheng, H, Hert, J, Schindler, T, Stahl, M, Robb, G, Crawford, JJ, Blaney, J, Montague, S, Leach, AG, Dossetter, AG and Griffen, EJ (2017) Learning Medicinal Chemistry Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) Rules from Cross-Company Matched Molecular Pairs Analysis (MMPA). Journal of Medicinal Chemistry. ISSN 0022-2623

Cox, PA, Reid, M, Leach, AG, Campbell, AD, King, EJ and Lloyd-Jones, GC (2017) Base-catalyzed Aryl-B(OH)2 Protodeboronation Revisited: from Concerted Proton-Transfer to Liberation of a Transient Arylanion. Journal of the American Chemical Society, 139 (37). ISSN 0002-7863

Davies, MJ, Leach, AG, Fullwood, DL, Mistry, D and Hope, A (2017) The pH Dependent Interaction between Nicotine and Simulated Pulmonary Surfactant Monolayers with Associated Molecular Modelling. Surface and Interface Analysis. ISSN 1096-9918

Islam, Y, Leach, AG, Coxon, CR, Downing, J, Platt, M, Pluchino, S and Ehtezazi, T (2017) Smart micellar systems for brain drug delivery. In: KTN Biopharmaceutical Formulation Group, 11 July 2017 - 11 July 2017, Mancheter.

DAVIES, MJ, Taylor, Z, Ren, J, Leach, AG and Gibbons, P (2017) Crystallisation of Aspirin via Simulated Pulmonary Surfactant Monolayers and Lung-Specific Additives. Surface and Interface Analysis. ISSN 1096-9918

Gonzalez, JA, Ogba, OM, Morehouse, GF, Rosson, N, Houk, KN, Leach, AG, Cheong, PH-Y, Burke, MD and Lloyd-Jones, GC (2016) MIDA boronates are hydrolysed fast and slow by two different mechanisms. Nature Chemistry, 8 (11). pp. 1067-1075. ISSN 1755-4330

Cox, PA, Leach, AG, Campbell, AD and Lloyd-Jones, GC (2016) Protodeboronation of Heteroaromatic, Vinyl, and Cyclopropyl Boronic Acids: pH-Rate Profiles, Autocatalysis, and Disproportionation. Journal of the American Chemical Society, 138 (29). pp. 9145-9157. ISSN 0002-7863

Noonan, G and Leach, AG (2015) A mechanistic proposal for the protodeboronation of neat boronic acids: boronic acid mediated reaction in the solid state. Organic and Biomolecular Chemistry, 13. pp. 2555-2560. ISSN 1477-0539