Article

Maasar, M-F, Turner, DC, Gorski, PP, Seaborne, RA, Strauss, JA, Shepherd, SO, Cocks, MS, Pillon, NJ, Zierath, JR, Hulton, AT, Drust, B and Sharples, AP (2021) The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle. Frontiers in Physiology, 12. ISSN 1664-042X

Turner, DC, Gorski, PP, Seaborne, RA, Viggars, M, Murphy, M, Jarvis, JC, Martin, NRW, Stewart, CE and Sharples, AP (2021) Mechanical loading of bioengineered skeletal muscle in vitro recapitulates gene expression signatures of resistance exercise in vivo. Journal of Cellular Physiology. ISSN 1097-4652

Hughes, D, Turner, DC, Baehr, LM, Seaborne, RA, Viggars, M, Jarvis, JC, Gorski, P, Stewart, CE, Owens, DJ, Bodine, S and Sharples, AP (2021) Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism. American Journal of Physiology: Cell Physiology, 320 (1). C45-C56. ISSN 0363-6143

Turner, DC, Gorski, PP, Maasar, MF, Seaborne, RA, Baumert, P, Brown, AD, Kitchen, MO, Erskine, RM, Dos-Remedios, I, Voisin, S, Eynon, N, Sultanov, RI, Borisov, OV, Larin, AK, Semenova, EA, Popov, DV, Generozov, EV, Stewart, CE, Drust, B, Owens, DJ et al, Ahmetov, II and Sharples, AP (2020) DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity. Scientific Reports, 10 (1). ISSN 2045-2322

Turner, DC, Gorski, PP, Maasar, MF, Seaborne, RA, Baumert, P, Brown, AD, Kitchen, MO, Erskine, RM, Dos-Remedios, I, Voisin, S, Eynon, N, Sultanov, RI, Borisov, OV, Larin, AK, Semenova, EA, Popov, DV, Generozov, EV, Stewart, CE, Drust, B, Owens, DJ et al, Ahmetov, II and Sharples, AP (2020) DNA methylation across the genome in aged human skeletal muscle tissue and stem cells: The role of HOX genes and physical activity. Scientific Reports, 10.

Hearris, MA, Hammond, KM, Seaborne, RA, Stocks, B, Shepherd, SO, Philp, A, Sharples, AP, Morton, JP and Louis, JB (2019) Graded reductions in pre-exercise muscle glycogen impair exercise capacity but do not augment cell skeletal muscle signalling: implication for CHO periodisation. Journal of Applied Physiology. ISSN 8750-7587

Seaborne, RA, Hughes, DC, Turner, DC, Owens, DJ, Baehr, LM, Gorski, P, Semenova, EA, Borisov, OV, Larin, AK, Popov, DV, Generozov, EV, Sutherland, H, Ahmetov, II, Jarvis, JC, Bodine, SC and Sharples, AP (2019) UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy. The Journal of Physiology. ISSN 0022-3751

Turner, DC, Seaborne, RA and Sharples, AP (2019) Comparative Transcriptome and Methylome Analysis in Human Skeletal Muscle Anabolism, Hypertrophy and Epigenetic Memory. Scientific Reports. ISSN 2045-2322

Seaborne, RA, Strauss, JA, Cocks, MS, Shepherd, SO, O'Brien, TD, van Someren, KA, Bell, PG, Murgatroyd, C, Morton, JP, Stewart, CE, Mein, CA and Sharples, AP (2018) Methylome of human skeletal muscle after acute & chronic resistance exercise training, detraining & retraining. Scientific Data, 5. ISSN 2052-4463

Seaborne, RA, Strauss, JA, Cocks, MS, Shepherd, SO, O'Brien, TD, van Someren, KA, Bell, PG, Murgatroyd, C, Morton, JP, Stewart, CE and Sharples, AP (2018) Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy. Scientific Reports, 8. ISSN 2045-2322

Fisher, A, Seaborne, RA, Hughes, TM, Gutteridge, A, Stewart, CE, Coulson, JM, Sharples, AP and Jarvis, JC (2017) Transcriptomic and Epigenetic Regulation of Disuse Atrophy and the Return to Activity in Skeletal Muscle. FASEB Journal, Epub A. ISSN 1530-6860

Sharples, AP, Stewart, CE and Seaborne, RA (2016) Does skeletal muscle have an ‘epi’-memory? The role of epigenetics in nutritional programming, metabolic disease, aging and exercise. Aging Cell. ISSN 1474-9726

Book Section

Turner, DC, Kasper, AM, Seaborne, RA, Brown, AD, Close, GL, Murphy, MF, Stewart, CE, Martin, NRW and Sharples, AP (2018) Exercising Bioengineered Skeletal Muscle In Vitro: Biopsy to Bioreactor. In: Myogenesis: Methods and Protocols. Springer, New York, pp. 55-79. ISBN 9781493988969

Thesis

Seaborne, RA (2018) The Role of DNA Methylation in the Regulation of Skeletal Muscle Atrophy, Hypertrophy and Epigenetic ‘Memory’. Doctoral thesis, Liverpool John Moores University.